We investigated the impact of dispersible zinc tablets on postoperative sore throat (POST) experienced by patients after endotracheal intubation. In our study, 88 patients were divided into two groups. One group received a 40 mg zinc tablet, while the other received a placebo 30 minutes before their surgery.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
Read More
9
Zinc reduces postoperative sore throat
The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study.
We explored the potential benefits of zinc lozenges for easing postoperative sore throat (POST), a common discomfort following endotracheal intubation. By conducting a randomized, double-blinded trial with 79 patients undergoing low- to moderate-risk surgeries, we divided participants into two groups: one received zinc lozenges, while the other was given a placebo.
Our findings revealed promising results. At the crucial four-hour mark post-surgery, only 7% of patients who took zinc experienced POST, compared to 29% in the placebo group. Interestingly, the difference was even more pronounced right after surgery, where the zinc group reported a 0% incidence of POST versus 24% for the control group.
Moreover, the severity of sore throat symptoms was notably less intense among those in the zinc group. Those with mild and moderate sore throat pains reported significantly lower severity scores. These results suggest that a single dose of 40 mg of zinc lozenges taken just 30 minutes before surgery can greatly aid in reducing both the occurrence and discomfort of POST in the early hours after surgery.
Read More
9.5
Zinc reduces postoperative sore throat
A randomised, double-blind, comparative study of preoperative magnesium sulphate versus zinc sulphate gargle for prevention of postoperative sore throat following endotracheal intubation.
We conducted a study to understand how well zinc can help prevent postoperative sore throat (POST) after endotracheal intubation. We compared the effects of gargling with zinc sulphate versus magnesium sulphate in a controlled trial involving 132 patients. Those in the zinc group received a solution with 40 mg of elemental zinc, while the magnesium group used 20 mg/kg of magnesium sulphate, with a control group receiving only dextrose.
Our findings showed that the group using zinc sulphate experienced notably lower rates of sore throat compared to those using magnesium sulphate. Specifically, the incidence of mild POST was significantly lower in the zinc group, especially during the first four hours after surgery. Overall, zinc gargle proved to be more effective in reducing sore throat compared to magnesium sulphate, demonstrating its potential benefits in postoperative care.
These results highlight the importance of zinc as a simple yet effective intervention to reduce discomfort for patients following surgery. By using zinc gargle preoperatively, we can potentially improve patient outcomes related to postoperative sore throat.
Read More
Most Useful Reviews
7.5
Effective against illness
5 people found this helpful
The best zinc on iHerb! Excellent, high-quality zinc in a small dosage (15 mg in one capsule), well absorbed, and does not cause nausea. Zinc is vital for immunity, especially during a pandemic! Taking 3-4 capsules at the initial stage of sore throat helps stop the disease's progression. I have tested this repeatedly on myself and loved ones. A course of zinc has improved my hair, skin, and nails. I highly recommend this particular product, it is really the best on iHerb!
Read More
9
Very effective product
Great quality zinc with 15 mg taken twice daily works wonders for me. I noticed its impressive effectiveness against viral infections; I experienced only a sore throat for less than 48 hours when I caught Covid. There’s no unpleasant aftertaste, making it an essential mineral for a robust immune system.
Read More
9
Effective during illness
An excellent supplement for immunity, zinc significantly aids with sore throat. I consistently use it during cold season and at the first signs of illness.
A randomised, double-blind, comparative study of preoperative magnesium sulphate versus zinc sulphate gargle for prevention of postoperative sore throat following endotracheal intubation.
We conducted a study to understand how well zinc can help prevent postoperative sore throat (POST) after endotracheal intubation. We compared the effects of gargling with zinc sulphate versus magnesium sulphate in a controlled trial involving 132 patients. Those in the zinc group received a solution with 40 mg of elemental zinc, while the magnesium group used 20 mg/kg of magnesium sulphate, with a control group receiving only dextrose.
Our findings showed that the group using zinc sulphate experienced notably lower rates of sore throat compared to those using magnesium sulphate. Specifically, the incidence of mild POST was significantly lower in the zinc group, especially during the first four hours after surgery. Overall, zinc gargle proved to be more effective in reducing sore throat compared to magnesium sulphate, demonstrating its potential benefits in postoperative care.
These results highlight the importance of zinc as a simple yet effective intervention to reduce discomfort for patients following surgery. By using zinc gargle preoperatively, we can potentially improve patient outcomes related to postoperative sore throat.
Read More
9.5
Zinc reduces postoperative sore throat
Preoperative oral zinc tablet decreases incidence of postoperative sore throat.
We investigated the impact of dispersible zinc tablets on postoperative sore throat (POST) experienced by patients after endotracheal intubation. In our study, 88 patients were divided into two groups. One group received a 40 mg zinc tablet, while the other received a placebo 30 minutes before their surgery.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
Read More
9
Zinc reduces postoperative sore throat
The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study.
We explored the potential benefits of zinc lozenges for easing postoperative sore throat (POST), a common discomfort following endotracheal intubation. By conducting a randomized, double-blinded trial with 79 patients undergoing low- to moderate-risk surgeries, we divided participants into two groups: one received zinc lozenges, while the other was given a placebo.
Our findings revealed promising results. At the crucial four-hour mark post-surgery, only 7% of patients who took zinc experienced POST, compared to 29% in the placebo group. Interestingly, the difference was even more pronounced right after surgery, where the zinc group reported a 0% incidence of POST versus 24% for the control group.
Moreover, the severity of sore throat symptoms was notably less intense among those in the zinc group. Those with mild and moderate sore throat pains reported significantly lower severity scores. These results suggest that a single dose of 40 mg of zinc lozenges taken just 30 minutes before surgery can greatly aid in reducing both the occurrence and discomfort of POST in the early hours after surgery.
Read More
8
Zinc's role in sore throat treatment
The Effectiveness of a Dietary Supplement with Honey, Propolis, Extract, and Zinc in Children Affected by Acute Tonsillopharyngitis: An Open, Randomized, and Controlled Trial.
We evaluated a promising dietary supplement that combines honey, propolis, and zinc to see how effective it could be for children suffering from acute tonsillopharyngitis, a type of sore throat. In this open-label, randomized, and controlled study, we compared the supplement along with standard care against standard care alone over six days.
The results revealed that incorporating the supplement with standard care led to notable improvements in certain symptoms associated with sore throat, such as throat pain and swallowing difficulties by day four and six. Although zinc was part of the blend, it was challenging to pinpoint its independent effect, given that it was studied alongside honey and propolis.
Interestingly, only one child in the standard care group needed additional medications like ibuprofen, highlighting that the supplement may reduce the need for further treatment. Importantly, we did not report any adverse events, making this combination a potential safe addition to treatment.
Overall, while the study presents encouraging results regarding the adjunctive use of the supplement in treating sore throat, it remains unclear how much zinc alone contributes to its effectiveness.
Read More
8
Zinc's variable effectiveness for sore throat
Zinc deficits, mucositis, and mucosal macrophage perturbation: is there a relationship?
We examined recent findings regarding zinc's impact on sore throat, particularly in post-operative settings. Some studies have reported that specific zinc formulations, like polaprezinc, can effectively reduce symptoms associated with sore throat after procedures like endotracheal intubation.
Importantly, zinc sulfate showed mixed results, with one review suggesting it did not significantly decrease the occurrence or intensity of oral mucositis in cancer patients. However, there are indications that certain zinc preparations may still hold promise in specific contexts, such as managing sore throat post-surgery.
Overall, while zinc's benefits in sore throat treatment appear to vary, ongoing research explores the best applications and formulations of zinc to potentially ease discomfort. As such, individuals seeking relief should keep an eye on emerging studies that could clarify zinc's role in throat health.
The best zinc on iHerb! Excellent, high-quality zinc in a small dosage (15 mg in one capsule), well absorbed, and does not cause nausea. Zinc is vital for immunity, especially during a pandemic! Taking 3-4 capsules at the initial stage of sore throat helps stop the disease's progression. I have tested this repeatedly on myself and loved ones. A course of zinc has improved my hair, skin, and nails. I highly recommend this particular product, it is really the best on iHerb!
Read More
9
Very effective product
Great quality zinc with 15 mg taken twice daily works wonders for me. I noticed its impressive effectiveness against viral infections; I experienced only a sore throat for less than 48 hours when I caught Covid. There’s no unpleasant aftertaste, making it an essential mineral for a robust immune system.
Read More
9
Effective during illness
An excellent supplement for immunity, zinc significantly aids with sore throat. I consistently use it during cold season and at the first signs of illness.
Read More
9
Boosts recovery speed
Now is the season for colds, and zinc plays a crucial role. It has an antioxidant effect and enhances resistance to infections. Zinc is beneficial for alleviating sore throat and hastens recovery from colds.
Read More
9
Well tolerated remedy
An excellent dietary supplement that’s well tolerated and genuinely works. At the onset of acute respiratory infections, I take it and feel great after 3-5 days. Symptoms vanish, and there’s no stomach discomfort. I even gave it to my daughter for her sore throat, and by morning, everything was better!
A sore throat, also known as pharyngitis, is a common condition characterized by pain, scratchiness, or irritation of the throat. It can occur as a result of various factors, including viral infections like the common cold or flu, bacterial infections such as strep throat, allergies, dry air, or even irritants like smoke and pollution. Symptoms often manifest as a sensation of discomfort during swallowing and may be accompanied by swelling, redness, or the presence of white patches on the tonsils or throat lining.
Most sore throats are mild and resolve on their own within a week or so, often treated with home remedies such as warm salt water gargles, lozenges, and hydration. However, if the sore throat is severe, persistent, or associated with other concerning symptoms such as high fever, difficulty swallowing, or difficulty breathing, it's essential to consult a healthcare professional, as this may indicate a more serious condition that requires medical intervention. Proper diagnosis and treatment are crucial, especially if a bacterial infection is suspected, as it may necessitate antibiotics for effective treatment.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been studied for its potential effects on the immune system, and some evidence suggests it may help alleviate sore throat symptoms. Particularly, zinc lozenges or syrups may shorten the duration of a sore throat when taken at the onset of symptoms. The reasoning behind this is that zinc can inhibit the replication of the virus responsible for the cold and boost immune response, thus potentially providing some relief.
However, it’s important to use zinc cautiously, as high doses can lead to side effects such as nausea or a bad taste in the mouth. Most health experts recommend opting for zinc in moderate doses, ideally through lozenges, which can also provide some soothing effects. While zinc might not be a cure-all, it can be a helpful part of a broader treatment plan that includes rest, hydration, and over-the-counter pain relievers. If your sore throat persists or is accompanied by other severe symptoms, consulting with a healthcare professional is advisable.
Based on user reviews, the timeline for seeing results with zinc supplements for sore throat varies, but many users report seeing improvements within just a few days. For instance, one user mentioned feeling great after 3-5 days of taking zinc at the onset of acute respiratory infections, with symptoms disappearing in that timeframe Read Review. Another user observed that their sore throat lasted less than 48 hours when they caught COVID-19 while using zinc Read Review.
Additionally, several reviews highlight the utility of zinc when taken at the first signs of illness, suggesting it can help stop the progression of a sore throat effectively. Users commonly report that they take zinc in combination with other vitamins such as C and D, resulting in quicker recovery times Read Review. While individual experiences may vary, a consensus suggests that if taken promptly, zinc may yield noticeable relief within a few days.
Recent scientific research suggests that a combination of honey, propolis, and zinc may be beneficial for managing sore throat symptoms, particularly in children suffering from acute tonsillopharyngitis. A study specifically highlighted the effectiveness of this supplement alongside standard care, showing improvements in throat pain and swallowing difficulties by days four and six [1]. While the study established a positive correlation, it is important to note that the independent effect of zinc was difficult to isolate, as it was studied in conjunction with honey and propolis. Nevertheless, the results indicate that this blend could potentially reduce the need for additional medications like ibuprofen, making it a safe adjunct to traditional treatment.
On the other hand, research focused on zinc alone presents mixed results. For instance, while some studies have demonstrated zinc’s effectiveness in reducing postoperative sore throat, particularly after endotracheal intubation [5], its impact on sore throat related to common colds was not conclusively significant [9]. Consequently, while the incorporation of zinc in various forms shows promise, its role in treating sore throat specifically lacks a definitive consensus. Therefore, while there is some support for certain formulations of zinc as a treatment adjunct, the evidence remains varied, necessitating further investigation to clarify its efficacy and specific applications in sore throat management.
Users report a variety of improvements in symptoms when taking zinc supplements, particularly for sore throats and viral infections. Many individuals have noted significant relief when using zinc at the first signs of illness. For instance, one reviewer mentioned that taking 3-4 capsules at the onset of a sore throat helped to effectively halt the progression of the illness Read Review. Another user shared that their sore throat lasted less than 48 hours during a COVID-19 infection, attributing this quick recovery to the zinc they were taking Read Review.
Moreover, users have indicated that regular use of zinc not only contributes to faster recovery from infections but also enhances overall well-being by improving hair, skin, and nails Read Review. When combined with vitamins C and D, many have reported an even quicker recovery time Read Review. Overall, while individual results can vary, the consensus among users suggests zinc may play a crucial role in alleviating sore throat symptoms and bolstering the immune response.
Users report positive outcomes when combining zinc with other supplements, particularly vitamins C and D, for managing sore throat symptoms. One reviewer emphasized that taking zinc alongside vitamin C and D at the first signs of illness resulted in a speedy recovery, noting the effectiveness of this combination Read Review. Another user mentioned taking zinc with their regular vitamin C, observing that their sore throat resolved more quickly than previous experiences, lasting only 5 days instead of 7 Read Review.
Additionally, users have generally praised zinc's role in enhancing overall immunity and expediting recovery from colds, making it a favored choice during the cold season. They consistently report using zinc as an integral part of their approach to manage sore throat symptoms, supporting its reputation as a beneficial supplement when combined effectively with others such as vitamin C Read Review.
Based on user reviews, a dose of Zinc around 15 mg appears to be effective for treating sore throat, with many users reporting positive experiences. For instance, one user mentioned taking 3-4 capsules of a 15 mg zinc supplement at the onset of a sore throat, stating it helped stop the disease's progression effectively Read Review. Others confirmed that taking 15 mg twice daily aided in mitigating symptoms during viral infections, with one user specifically noting that their sore throat lasted less than 48 hours when they took Zinc while experiencing Covid symptoms Read Review.
Several reviews also emphasize the importance of taking Zinc at the first signs of illness, suggesting that early intervention can lead to quicker recovery Read Review. Additionally, users combined Zinc with vitamins C and D to enhance its effectiveness, noting a speedy recovery when symptoms appeared Read Review. Overall, a dosage of around 15 mg, taken either as needed or consistently during cold season, seems to provide significant relief for sore throat symptoms.
9
Well tolerated remedy
An excellent dietary supplement that’s well tolerated and genuinely works. At the onset of acute respiratory infections, I take it and feel great after 3-5 days. Symptoms vanish, and there’s no stomach discomfort. I even gave it to my daughter for her sore throat, and by morning, everything was better!
9
Very effective product
Great quality zinc with 15 mg taken twice daily works wonders for me. I noticed its impressive effectiveness against viral infections; I experienced only a sore throat for less than 48 hours when I caught Covid. There’s no unpleasant aftertaste, making it an essential mineral for a robust immune system.
7.5
Improved recovery speed
Excellent, natural zinc product with no side effects! I take two pills at the first signs of sore throat or cold, paired with vitamin C and D, leading to speedy recovery. I'm pleased with the effectiveness of this combination.
7.5
Effective against illness
5 people found this helpful
The best zinc on iHerb! Excellent, high-quality zinc in a small dosage (15 mg in one capsule), well absorbed, and does not cause nausea. Zinc is vital for immunity, especially during a pandemic! Taking 3-4 capsules at the initial stage of sore throat helps stop the disease's progression. I have tested this repeatedly on myself and loved ones. A course of zinc has improved my hair, skin, and nails. I highly recommend this particular product, it is really the best on iHerb!
6
Reduced symptoms time
Recently, I caught a cold with a runny nose and sore throat. I tried zinc along with my regular vitamin C. While unsure of its influence, my sore throat and nasal discomfort lasted only 5 days instead of 7. The capsules were comfortable to take, twice daily as advised.
9
Effective during illness
An excellent supplement for immunity, zinc significantly aids with sore throat. I consistently use it during cold season and at the first signs of illness.
8
Zinc's role in sore throat treatment
The Effectiveness of a Dietary Supplement with Honey, Propolis, Extract, and Zinc in Children Affected by Acute Tonsillopharyngitis: An Open, Randomized, and Controlled Trial.
We evaluated a promising dietary supplement that combines honey, propolis, and zinc to see how effective it could be for children suffering from acute tonsillopharyngitis, a type of sore throat. In this open-label, randomized, and controlled study, we compared the supplement along with standard care against standard care alone over six days.
The results revealed that incorporating the supplement with standard care led to notable improvements in certain symptoms associated with sore throat, such as throat pain and swallowing difficulties by day four and six. Although zinc was part of the blend, it was challenging to pinpoint its independent effect, given that it was studied alongside honey and propolis.
Interestingly, only one child in the standard care group needed additional medications like ibuprofen, highlighting that the supplement may reduce the need for further treatment. Importantly, we did not report any adverse events, making this combination a potential safe addition to treatment.
Overall, while the study presents encouraging results regarding the adjunctive use of the supplement in treating sore throat, it remains unclear how much zinc alone contributes to its effectiveness.
9.5
Zinc reduces postoperative sore throat
Preoperative oral zinc tablet decreases incidence of postoperative sore throat.
We investigated the impact of dispersible zinc tablets on postoperative sore throat (POST) experienced by patients after endotracheal intubation. In our study, 88 patients were divided into two groups. One group received a 40 mg zinc tablet, while the other received a placebo 30 minutes before their surgery.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
7
Zinc's effects on sore throat
Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial.
We conducted a rigorous study to see how zinc acetate lozenges might help reduce the painful and annoying symptoms of the common cold, particularly sore throats. In a well-structured environment, we recruited 50 volunteers who started experiencing cold symptoms within the last 24 hours. Participants were randomly assigned to receive either zinc lozenges or a placebo, taking one every few hours during the day.
Over the course of the study, we monitored various symptoms, including sore throat, and measured participants' plasma zinc and cytokine levels on the first day and as they recovered. We observed that those who took zinc lozenges experienced a shorter duration of cold symptoms, with cough showing notable improvement.
However, when it came to sore throats specifically, while there were positive results, the changes didn't stand out as significantly different from those who received the placebo. So, while zinc may play a role in easing cold symptoms overall, its particular impact on sore throat isn’t conclusively proven in our findings.
References
Cardinale F, Barattini DF, Martinucci V, Bordea MM, Barattini L, et al. The Effectiveness of a Dietary Supplement with Honey, Propolis, Extract, and Zinc in Children Affected by Acute Tonsillopharyngitis: An Open, Randomized, and Controlled Trial. Pharmaceuticals (Basel). 2024;17. doi:10.3390/ph17060804
Cardinale F, Barattini DF, Sbrocca F, Centi A, Giuntini G, et al. The Effects of a Dietary Supplement (PediaFlù) Plus Standard of Care in Children With Acute Tonsillopharyngitis/Rhinopharyngitis: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2024;13:e53703. doi:10.2196/53703
Bhanwra A, Palta S, Saroa R, Saxena P, Bhanwra S, et al. Role of preoperative zinc, magnesium and budesonide gargles in Postoperative Sore Throat (POST) - a randomised control trial. BMC Anesthesiol. 2024;24:164. doi:10.1186/s12871-024-02534-5
Mondal AK, Maiti AK, Chattopadhyay S, Bhar D. A randomised, double-blind, comparative study of preoperative magnesium sulphate versus zinc sulphate gargle for prevention of postoperative sore throat following endotracheal intubation. Indian J Anaesth. 2023;67:S261. doi:10.4103/ija.ija_975_22
Sarkar T, Mandal T. Preoperative oral zinc tablet decreases incidence of postoperative sore throat. Indian J Anaesth. 2020;64:409. doi:10.4103/ija.IJA_959_19
Thomsen M, Vitetta L. Zinc deficits, mucositis, and mucosal macrophage perturbation: is there a relationship?. Curr Opin Clin Nutr Metab Care. 2019;22:365. doi:10.1097/MCO.0000000000000588
Farhang B, Grondin L. The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study. Anesth Analg. 2018;126:78. doi:10.1213/ANE.0000000000002494
Sun GB, Sun N, Tang HH, Zhu QB, Wen W, et al. Zinc sulfate therapy of vocal process granuloma. Eur Arch Otorhinolaryngol. 2012;269:2087. doi:10.1007/s00405-012-1971-1
Prasad AS, Fitzgerald JT, Bao B, Beck FW, Chandrasekar PH. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2000;133:245.